POEMS Syndrome: Nosographic classification and considerations on a clinical case


POEMS syndrome is a rare multisystemic disease characterised by the coexistence of two main symptoms, polyneuropathy and monoclonal gammopathy, associated with minor symptoms such as organomegaly, endocrinopathy, and skin changes. We describe a patient who presented with symptoms and signs fulfilling the criteria of POEMS. We have carried out a literature review with particular emphasis on its demographic and polymorphic clinical features.


Keywords: POEMS, monoclonal gammopathy, calciphylaxis, Castleman’s disease, VEGF

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