![](https://giornaleitalianodinefrologia.it/wp-content/uploads/sites/3/2018/01/Figure-20-Small.jpg?x85047)
Figure 20 (Small)
Figure 20. (Left) George Hitchins (1905-1988) and Trudy Elion (1918-1999) at Burroughs Wellcome labs in Tuckahoe NJ. Picture courtesy Burroughs Wellcome) (Right) George Schwartz (1928- fl.) who studied their first purine antimetabolite, 6-mercaptopurine (6-MP) an analogue of hypoxanthine, in the 1950s and showed it depressed immune responses. Hitchins and Elion received the Nobel prize for their work on antimetabolites to treat cancer.