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Protected: Successful Unconventional Treatment of Serratia Marcescens Exit-Site Infection in a Central Venous Catheter for Hemodialysis: A Case Report

Posted on Wednesday November 27th, 2024Scarica PDF

Sara Morales Palomares

DOI: 10.69097/41-06-2024-05

Silvia Cappelletti¹, Sara Morales Palomares², Stefano Mancin³, Marco Sguanci⁴

1 Department of Nephrology and Dialysis, Sant’Anna Hospital, Territorial Social Health Company Lariana, Como, Italy
2 Department of Pharmacy, Health and Nutritional Sciences (DFSSN), University of Calabria, Rende, Italy
3 Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Viale Montpellier, 1- 00128 Rome, Italy
4 A.O. Polyclinic San Martino Hospital, Genova

Corresponding author:
Sara Morales Palomares RN, PhD,
Department of Pharmacy, Health and Nutritional Sciences (DFSSN)
University of Calabria, Rende, Italy
Phone: +39 3404249439
Mail: sara.morales@unical.it

Abstract

Introduction. Central Catheter-related infections and biofilm formation are significant issues in the context of nosocomial infections that increase resistance to conventional therapies.
Methodology. This case report describes an unconventional treatment for a Serratia Marcescens Central Venous Catheter infection in a hemodialysis patient through the combination of polyguanide and betaine. Clinical evaluations were conducted using the Visual Exit-Site Score and culture swabs.
Results. After the first four treatment sessions there was a significant reduction in redness and pain (VES=1); the culture swab at the end of treatment was negative.
Conclusions. The results of this case report encourage further research on the effectiveness of non-antibiotic treatments.

Keywords: Exit-Site infection, Central Venous Catheter, Serratia Marcescens, Polyguanide, Betaine